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Scientific Newsletter


Retinal Proteins
Not Involved In Retinal Disorders

Recent update from: 21.04.2001


Proteins involved in the control of the visual cascade.
This page summarizes data on human proteins involved in the control and regulation of the visual cascade .
If you click on a protein on the right, you will find listings of data on this protein and further pages providing information from internet databases on that protein can be accessed. These data include information on animal proteins too.

Phosducin
Human Data
Source data from literature
on this protein can be obtained here.
Editor's Notes
Subunit Subunits Aminoacids Modifications









Mr / Weight Cofactors / Substrates




Exons Transcripts Regulatory Elements





Markers / RFLPs Primers Assignment




General Data


PROTEIN DATA

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Protein Subtype Locus Species EC-No. Swissprot PIR Prosite
Phosducin
PHD Bos taurus EC- Q28160 A38379 A38378 JH0215
Phosducin
PHD Felis catus EC- P41686 A34867 A34868 PS00295
Phosducin
PDC Homo sapiens EC- P20941 A35422 JH0214
Phosducin
PDC Mus musculus EC-
JC2018
Phosducin pineal PDC Rattus norvegicus EC-
A39903 JH0217
Phosducin retinal PDC Rattus norvegicus EC-
JH0216


GENE DATA

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Gene Subtype Locus Species Genbank Unigene Medline
Phosducin
PHD Bos taurus M58170 M33529
90368806 91007277
Phosducin
pdc Canis familiaris AF046874

Phosducin
PHD Felis catus L35314 M30177 M30140

Phosducin
PDC Homo sapiens L25260 M33478 M38059 M60720 M38058 NM_002597 Hs.550 94040308 91007277
Phosducin
PDC Mus musculus L20420 L08075
94040808 94009395
Phosducin pineal PDC Rattus norvegicus M60738 M61147 M61148 M61149 M61150 J04790
90368806 91301696
Phosducin retinal PDC Rattus norvegicus M33530 M33528 NM_012872 Rn.9739 91007277


GENE LOCUS DATA

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Gene Subtype Locus Species Genome Database Mouse Genome Database OMIM Locus Link
Phosducin
PDC Homo sapiens 125268
171490 5132
Phosducin
PDC Mus musculus
Rpr1

Phosducin retinal PDC Rattus norvegicus


25343


Retina-specific Phospholipases
Human Data


Subunit Subunits Aminoacids Modifications




isoform A2, cytosolic



Mr / Weight Cofactors / Substrates
isoform A2, cytosolic


Exons Transcripts Regulatory Elements
isoform A2, cytosolic



Markers / RFLPs Primers Assignment
isoform A2, cytosolic CA-Repeat For CA-Repeat 1q25

General Data


PROTEIN DATA

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Protein Subtype Locus Species EC-No. Swissprot PIR Prosite
Phospholipase type A2 PLA2 Bos taurus EC 3.1.1.4


Phospholipase type A2 PLA2 Homo sapiens EC 3.1.1.4
A49959 A39329 B56395
Phospholipase MPL2-8 PLA2 Mus musculus EC 3.1.1.4
A54762 I49353 B39898 B54762 C60718
Phospholipase RPLA2-8 PLA2 Rattus norvegicus EC 3.1.1.4
JU0283 A33394 B54762


GENE DATA

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Gene Subtype Locus Species Genbank Unigene Medline
Phospholipase type A2 PLA2 Homo sapiens U11239 D38176 D38177 D38178 Z33877 NM_000928 AH002940 AC003982 M21054 Hs.992 95301280 95166651 91331987 95098632 91256305 95091788


GENE LOCUS DATA

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Gene Subtype Locus Species Genome Database Mouse Genome Database OMIM Locus Link
Phospholipase type A2 PLA2 Homo sapiens 120296
172410 172411 600522 601192 601658 5319


Protein Kinase C
Human Data
Source data from literature
on this protein can be obtained here.
Editor's Notes
Subunit Subunits Aminoacids Modifications
  1. isoform alpha (PRKCA)
  2. isoform beta 1 (PRKCB1)
  3. isoform gamma (PRKCG)
    brain specific
  4. isoform delta (PRKCD)
  5. isoform iota (PRKCI)
    in kidney, muscle, lung, brain
  6. isoform theta (PRKCQ)
    in lymphoid tissues
    particular T cells
    hematopoietic stem cell lines
  7. isoform zeta (PRKCZ)
  1. 1
  2. 1
  3. 1
  4. 1
  5. 1
  6. 1
  7. 1
  1. -
  2. 673 AA
  3. 697 AA
  4. -
  5. 587 AA
  6. -
  7. 592 AA
  1. Autophosphorylated
  2. Autophosphorylated
  3. Autophosphorylated
  4. Autophosphorylated
  5. Autophosphorylated
  6. Autophosphorylated
  7. Autophosphorylated

Mr / Weight Cofactors / Substrates
  1. isoform alpha (PRKCA)
  2. isoform beta 1 (PRKCB1)
  3. isoform gamma (PRKCG)
    brain specific
  4. isoform delta (PRKCD)
  5. isoform iota (PRKCI)
    in kidney, muscle, lung, brain
  6. isoform theta (PRKCQ)
    in lymphoid tissues
    particular T cells
    hematopoietic stem cell lines
  7. isoform zeta (PRKCZ)
  1. -
  2. 76,9 kDa
  3. 78,4 kDa
  4. -
  5. -
  6. 80 kDa
  1. Ca2+
    Diacylglycerol
    Phosphatidylserine
    Phosphatidylinositol
  2. Ca2+
    Diacylglycerol
    Phosphatidylserine
    Phosphatidylinositol
  3. Ca2+
    Diacylglycerol
    Phosphatidylserine
    Phosphatidylinositol
  4. Diacylglycerol
    Phosphatidylserine
    Phosphatidylinositol
  5. -
  6. -
  7. Diacylglycerol
    Phosphatidylserine
    Phosphatidylinositol

Exons Transcripts Regulatory Elements
  1. isoform alpha (PRKCA)
  2. isoform beta 1 (PRKCB1)
  3. isoform gamma (PRKCG)
    brain specific
  4. isoform delta (PRKCD)
  5. isoform iota (PRKCI)
    in kidney, muscle, lung, brain
  6. isoform theta (PRKCQ)
    in lymphoid tissues
    particular T cells
    hematopoietic stem cell lines
  7. isoform zeta (PRKCZ)

Markers / RFLPs Primers Assignment
  1. isoform alpha (PRKCA)
  2. isoform beta 1 (PRKCB1)
  3. isoform gamma (PRKCG)
    brain specific
  4. isoform delta (PRKCD)
  5. isoform iota (PRKCI)
    in kidney, muscle, lung, brain
  6. isoform theta (PRKCQ)
    in lymphoid tissues
    particular T cells
    hematopoietic stem cell lines
  7. isoform zeta (PRKCZ)
  1. 17q22-24
  2. 16q11.2
  3. 19q13
  4. 3p
  5. Xq21.3
  6. 10q15

General Data


PROTEIN DATA

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Protein Subtype Locus Species EC-No. Swissprot PIR Prosite
Protein Kinase C alpha PRKCA Bos taurus EC 2.7.1.-
A00621
Protein Kinase C beta-II PRKB2 Bos taurus EC 2.7.1.-
A24664
Protein Kinase C gamma PRKCG Bos taurus EC 2.7.1.-
C24664
Protein Kinase C
PRKC Drosophila melanogaster EC 2.7.1.-
B32392 A32392 A32545
Protein Kinase C alpha PRKCA Homo sapiens EC 2.7.1.-
S09496
Protein Kinase C beta1 PRKCB1 Homo sapiens EC 2.7.1.-
S00159 I38118 B29583 I55365 I38117 B24664 A29583 S01626 I38119 A24159
Protein Kinase C beta-II PRKCB2 Homo sapiens EC 2.7.1.-
S00159 I38118 B29583 I55365 I38117
Protein Kinase C delta PRKCD Homo sapiens EC 2.7.1.-
S65016 S35704 S35705
Protein Kinase C delta 13 PRKC Homo sapiens EC 2.7.1.- P17252 S35704 S35705 S65016 S09496 PS00107 PS00108 PS00479 PS50011 PS00499 PS50004
Protein Kinase C epsilon PRKCE Homo sapiens EC 2.7.1.-
S28942
Protein Kinase C eta PRKCH Homo sapiens EC 2.7.1.-
A39666 A42131 S65018
Protein Kinase C gamma PRKCG Homo sapiens EC 2.7.1.-
D24664 S31611 S36837
Protein Kinase C iota PRKCI Homo sapiens EC 2.7.1.-
A49509 I54207
Protein Kinase C mu PRKCM Homo sapiens EC 2.7.1.-


Protein Kinase C theta PRKCQ Homo sapiens EC 2.7.1.-
A45416 A47160
Protein Kinase C zeta PRKCZ Homo sapiens EC 2.7.1.-
JN0877 S25605 S36836
Protein Kinase C alpha PRKCA Mus musculus EC 2.7.1.-
S7104 JS0078
Protein Kinase C beta1 PRKCB1 Mus musculus EC 2.7.1.-
B24664 A29583 S01626 I38119 A42159
Protein Kinase C beta-II PRKB2 Mus musculus EC 2.7.1.-
S11213
Protein Kinase C delta PRKCD Mus musculus EC 2.7.1.-
A40281 S19709
Protein Kinase C epsilon PRKCE Mus musculus EC 2.7.1.-
S02270
Protein Kinase C eta PRKC Mus musculus EC 2.7.1.-
A23690
Protein Kinase C gamma PRKCG Mus musculus EC 2.7.1.-
JN0548 S20735 S29620
Protein Kinase C lambda PRKC Mus musculus EC 2.7.1.-
A53758
Protein Kinase C theta PRKCQ Mus musculus EC 2.7.1.-
A44500
Protein Kinase C zeta PRKCZ Mus musculus EC 2.7.1.-
JC1480
Protein Kinase C alpha PRKCA Oryctolagus cuniculus EC 2.7.1.-
C26037
Protein Kinase C beta-I PRKCB1 Oryctolagus cuniculus EC 2.7.1.-
B26037
Protein Kinase C beta-II PRKB2 Oryctolagus cuniculus EC 2.7.1.-
A26037
Protein Kinase C epsilon PRKCE Oryctolagus cuniculus EC 2.7.1.-
A29880
Protein Kinase C gamma PRKCG Oryctolagus cuniculus EC 2.7.1.-
A28708
Protein Kinase C alpha PRKCA Rattus norvegicus EC 2.7.1.-
S02248 S02620
Protein Kinase C beta1 PRKCB1 Rattus norvegicus EC 2.7.1.-
I53460 A26408 A00622 A28423 A05107
Protein Kinase C betaII PRKB2 Rattus norvegicus EC 2.7.1.-
A00623 A05106 A38237 A38238 A43621
Protein Kinase C delta PRKCD Rattus norvegicus EC 2.7.1.-
A28163 S17832 S00215
Protein Kinase C epsilon PRKCE Rattus norvegicus EC 2.7.1.-
B28163 B26408 S00216
Protein Kinase C eta PRKC Rattus norvegicus EC 2.7.1.-
S29478 I60246
Protein Kinase C gamma PRKCG Rattus norvegicus EC 2.7.1.-
A05105 S02129 I55317
Protein Kinase C zeta PRKCZ Rattus norvegicus EC 2.7.1.-
A30314 C28163 S00217
Protein Kinase C I PRKC Xenopus laevis EC 2.7.1.-
A37237 B37237


GENE DATA

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Gene Subtype Locus Species Genbank Unigene Medline
Protein Kinase C alpha PRKCA Homo sapiens NM_002737 X52479 Hs.169449
Protein Kinase C beta1 PRKCB1 Homo sapiens NM_002738 X06318 X07109 Hs.77202
Protein Kinase C delta PRKCD Homo sapiens D10495 D90470 L07860 L07861 NM_006254 Hs.155342 98087154 98087154
Protein Kinase C delta 13 PRKC Homo sapiens X52479 M22199
90245676 87217094 91332033
Protein Kinase C epsilon PRKCE Homo sapiens NM_005400 X65293 Hs.211592
Protein Kinase C eta PRKCH Homo sapiens NM_006255 AF045569 M55284 Hs.1880
Protein Kinase C gamma PRKCG Homo sapiens M13977 Z15114 Hs.2890
Protein Kinase C iota PRKCI Homo sapiens NM_002740 L18964 L33881 Hs.1904
Protein Kinase C mu PRKCM Homo sapiens NM_002742 X75756 Hs.2891
Protein Kinase C theta PRKCQ Homo sapiens NM_006257 L01087 L07032 Hs.211593
Protein Kinase C zeta PRKCZ Homo sapiens NM_002744 L14283 Z15108 Hs.78793
Protein Kinase C alpha PRKCA Rattus norvegicus X07286

Protein Kinase C beta1 PRKCB1 Rattus norvegicus NM_012713 U62762 M19007 Rn.9745
Protein Kinase C gamma PRKCG Rattus norvegicus M55417 J05664 M13707 NM_012628 Rn.9747 91060619


GENE LOCUS DATA

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Gene Subtype Locus Species Genome Database Mouse Genome Database OMIM Locus Link
Protein Kinase C alpha PRKCA Homo sapiens

176960 5578
Protein Kinase C beta1 PRKCB1 Homo sapiens 128016
176970 5579
Protein Kinase C delta PRKCD Homo sapiens 128038
176977 5580
Protein Kinase C delta 13 PRKC Homo sapiens 128015


Protein Kinase C epsilon PRKCE Homo sapiens 128039
176975 5581
Protein Kinase C eta PRKCH Homo sapiens 129009

5583
Protein Kinase C gamma PRKCG Homo sapiens 128017
176980 5582
Protein Kinase C iota PRKCI Homo sapiens 266533
300094 5584
Protein Kinase C mu PRKCM Homo sapiens 330794

5587
Protein Kinase C theta PRKCQ Homo sapiens 136263
600448 5588
Protein Kinase C zeta PRKCZ Homo sapiens 128040
176982 5590
Protein Kinase C alpha PRKCA Rattus norvegicus


24680
Protein Kinase C beta1 PRKCB1 Rattus norvegicus


25023
Protein Kinase C gamma PRKCG Rattus norvegicus


24681


Prenyl Transferases
Human Data
Source data from literature
on this protein can be obtained here.
Editor's Notes
Subunit Subunits Aminoacids Modifications





Mr / Weight Cofactors / Substrates




Exons Transcripts Regulatory Elements





Markers / RFLPs Primers Assignment





PROTEIN DATA

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Protein Subtype Locus Species EC-No. Swissprot PIR Prosite
Geranyl-Geranylyl transferase beta GGtaseI Drosophila melanogaster EC 2.5.1.-


Geranyl-Geranylyl transferase beta GGTaseI Homo sapiens EC 2.5.1.-


Geranyl-Geranylyl transferase comp. B, alpha RABGGTA Homo sapiens EC 2.5.1.- P53611

Geranyl-Geranylyl transferase comp. B, beta RABGGTB Homo sapiens EC 2.5.1.- P53611 Q92697 G02431
Geranyl-Geranylyl transferase comp. B, beta GGTaseII Mus musculus EC 2.5.1.- P53612 I49116
Geranyl-Geranylyl transferase beta GGTaseI Rattus norvegicus EC 2.5.1.-


Geranyl-Geranylyl transferase comp. B, alpha GGTaseII Rattus norvegicus EC 2.5.1.- Q08602 A45977
Geranyl-Geranylyl transferase comp. B, beta GGTaseII Rattus norvegicus EC 2.5.1.- Q08603 B45977


GENE DATA

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Gene Subtype Locus Species Genbank Unigene Medline
Geranyl-Geranylyl transferase beta GGtaseI Drosophila melanogaster U43587 U43588

Geranyl-Geranylyl transferase beta GGTaseI Homo sapiens L25441 G13524 Z85996

Geranyl-Geranylyl transferase comp. B, alpha RABGGTA Homo sapiens Y08200 NM_004581 Hs.78920 97127587
Geranyl-Geranylyl transferase comp. B, beta RABGGTB Homo sapiens T25892 U49245 X98001 Y08201 AI731903 NM_004582 Hs.78948 97127587 96314492
Geranyl-Geranylyl transferase comp. B, beta GGTaseII Mus musculus U12922 NM_011231 Mm.29211 95374956
Geranyl-Geranylyl transferase beta GGTaseI Rattus norvegicus L24116 AU050790

Geranyl-Geranylyl transferase comp. B, alpha GGTaseII Rattus norvegicus S62096
93280201
Geranyl-Geranylyl transferase comp. B, beta GGTaseII Rattus norvegicus L10416 S62097 NM_013020
93280201


GENE LOCUS DATA

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Gene Subtype Locus Species Genome Database Mouse Genome Database OMIM Locus Link
Geranyl-Geranylyl transferase comp. B, alpha RABGGTA Homo sapiens 3793223
601905 5875
Geranyl-Geranylyl transferase comp. B, beta RABGGTB Homo sapiens 9621945
179080 5876
Geranyl-Geranylyl transferase comp. B, beta GGTaseII Mus musculus


19352
Geranyl-Geranylyl transferase comp. B, beta GGTaseII Rattus norvegicus


25533


Protein Phosphatase 2a

Human Data
Source data from literature
on this protein can be obtained here.
Editor's Notes
Subunit Subunits Aminoacids Modifications
  1. isoform 2A, catalytic alpha
  2. isoform 2A, catalytic beta
  3. isoform of EF-hand type, rdgC homologue
  4. PPP2R5A, regulatory
  5. PPP2R5B, regulatory
  6. PPP2R5C, regulatory
  7. PPP2R5D, regulatory
  8. PPP2R5E, regulatory
  1. 3
  2. 3
  3. 3
  4. 3
  5. 3
  6. 3
  7. 3
  1. 653 AA

Mr / Weight Cofactors / Substrates
  1. isoform 2A, catalytic alpha
  2. isoform 2A, catalytic beta
  3. isoform of EF-hand type, rdgC homologue
  4. PPP2R5A, regulatory
  5. PPP2R5B, regulatory
  6. PPP2R5C, regulatory
  7. PPP2R5D, regulatory
  8. PPP2R5E, regulatory

Exons Transcripts Regulatory Elements
  1. isoform 2A, catalytic alpha
  2. isoform 2A, catalytic beta
  3. isoform of EF-hand type, rdgC homologue
  4. PPP2R5A, regulatory
  5. PPP2R5B, regulatory
  6. PPP2R5C, regulatory
  7. PPP2R5D, regulatory
  8. PPP2R5E, regulatory
  1. 16

Markers / RFLPs Primers Assignment
  1. isoform 2A, catalytic alpha
  2. isoform 2A, catalytic beta
  3. isoform of EF-hand type, rdgC homologue
  4. PPP2R5A, regulatory
  5. PPP2R5B, regulatory
  6. PPP2R5C, regulatory
  7. PPP2R5D, regulatory
  8. PPP2R5E, regulatory
  1. 5q23-31
  2. 8p12-11.2
  3. Xp22
  4. 1q14
  5. 11q12
  6. 3p21
  7. 6p21.1
  8. 7p12-11.2

General Data


PROTEIN DATA

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Protein Subtype Locus Species EC-No. Swissprot PIR Prosite
Protein Phosphatase catalytic
Bos taurus EC 3.1.6.16 P05323 A28029 A35984 S01986 S00104 A27436 A32143 A37135 S10371 S32226 PS00125
Protein Phosphatase catalytic alpha
Bos taurus EC 3.1.6.16
S10371 S32226
Protein Phosphatase regulatory 65K
Bos taurus EC 3.1.6.16
D34541
Protein Phosphatase catalytic
Drosophila melanogaster EC 3.1.6.16 P23696 S12961 PS00125
Protein Phosphatase regulatory
Drosophila melanogaster EC 3.1.6.16
A46300 B45778
Protein Phosphatase regulatory 65K
Drosophila melanogaster EC 3.1.6.16


Protein Phosphatase regulatory PR55
Drosophila melanogaster EC 3.1.6.16
B45778 A46300
Protein Phosphatase catalytic alpha
Homo sapiens EC 3.1.6.16
S01986 A37135 A32143
Protein Phosphatase catalytic beta
Homo sapiens EC 3.1.6.16


Protein Phosphatase regulatory PPP2R5E Homo sapiens EC 3.1.6.16


Protein Phosphatase regulatory PPP2R5D Homo sapiens EC 3.1.6.16
A38351 A34541 C38351 B38351 D38351
Protein Phosphatase regulatory PPP2R5C Homo sapiens EC 3.1.6.16
B47114
Protein Phosphatase regulatory PPP2R5B Homo sapiens EC 3.1.6.16
S68686 S74311
Protein Phosphatase regulatory PPP2R5A Homo sapiens EC 3.1.6.16
A47114 B47114 C47114
Protein Phosphatase regulatory 130K
Homo sapiens EC 3.1.6.16


Protein Phosphatase regulatory 55K
Homo sapiens EC 3.1.6.16
A38351 B38351 E38351 C38351 D38351 A36180
Protein Phosphatase regulatory 65K
Homo sapiens EC 3.1.6.16
A34541 B34541 E38351 A36180 C34541 D34541
Protein Phosphatase regulatory PR13
Homo sapiens EC 3.1.6.16
B47114
Protein Phosphatase regulatory PR72
Homo sapiens EC 3.1.6.16
A47114
Protein Phosphatase catalytic beta
Mus musculus EC 3.1.6.16
B47187
Protein Phosphatase regulat. alpha
Mus musculus EC 3.1.6.16
A47187 B47187
Protein Phosphatase catalytic alpha
Oryctolagus cuniculus EC 3.1.6.16
S00104 S18812 A60240
Protein Phosphatase catalytic beta
Oryctolagus cuniculus EC 3.1.6.16 P11611 S00220 PS00125
Protein Phosphatase regulatory 55K
Oryctolagus cuniculus EC 3.1.6.16
A60240 S00104 A60240
Protein Phosphatase regulatory PR72
Oryctolagus cuniculus EC 3.1.6.16
C47114
Protein Phosphatase catalytic
Ovies aries EC 3.1.6.16


Protein Phosphatase catalytic
Rattus norvegicus EC 3.1.6.16


Protein Phosphatase catalytic alpha
Rattus norvegicus EC 3.1.6.16
S06592 JS0060 PS0311 A36491
Protein Phosphatase catalytic beta
Rattus norvegicus EC 3.1.6.16
A31357 S08486 S06593 B36491
Protein Phosphatase regulatory
Xenopus laevis EC 3.1.6.16
S20348
Protein Phosphatase regulatory 55k
Xenopus laevis EC 3.1.6.16


Protein Phosphatase regulatory 65k
Xenopus laevis EC 3.1.6.16



GENE DATA

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Gene Subtype Locus Species Genbank Unigene Medline
Protein Phosphatase catalytic
Bos taurus M16968 X72858 X52554 M60483 M36951 06087 M20192 X12646 J03804
87260892
Protein Phosphatase catalytic alpha
Bos taurus

91085575
Protein Phosphatase catalytic
Drosophila melanogaster X55199
91086675 91085575
Protein Phosphatase regulatory 55K
Drosophila melanogaster L12544 L07581 L07582 L07583 L07584 L07585 L07586
93177843
Protein Phosphatase regulatory 65K
Drosophila melanogaster M86442

Protein Phosphatase catalytic alpha
Homo sapiens M64929 J05328
96411660 91198016 96064678
Protein Phosphatase catalytic beta
Homo sapiens L42373 M60483 M60484 J05328 J05297 M64930
91105105 91198016 96064678 96411660
Protein Phosphatase regulatory PPP2R5B Homo sapiens L42374 NM_006244 Z69028 Hs.75199 96411660 93315512 96064678
Protein Phosphatase regulatory PPP2R5A Homo sapiens NM_006243 L42373 Hs.155079 96411660
Protein Phosphatase regulatory PPP2R5E Homo sapiens L76703 NM_006246 Z69029 Hs.173328 96411660 96355607
Protein Phosphatase regulatory PPP2R5D Homo sapiens L76702 NM_006245 AB000634 Hs.118244 96159032 96355607
Protein Phosphatase regulatory PPP2R5C Homo sapiens L42375 NM_002719 D26445 U37352 Hs.171734 96411660
Protein Phosphatase regulatory 130K
Homo sapiens L07590
93315512
Protein Phosphatase regulatory 55K
Homo sapiens L12146
93315512
Protein Phosphatase regulatory 65K
Homo sapiens M65254
90241887
Protein Phosphatase regulatory Ppp2r5e Mus musculus U49728

Protein Phosphatase regulatory Ppp2r5c Mus musculus U59418 Mm.3785
Protein Phosphatase catalytic alpha
Oryctolagus cuniculus X06087 M27611
87304854
Protein Phosphatase catalytic beta
Oryctolagus cuniculus M64931 Y00763 J05328
88083628 89078593 91198016
Protein Phosphatase catalytic
Ovies aries AF034549

Protein Phosphatase catalytic
Rattus norvegicus X14159
89051001
Protein Phosphatase regulatory 55k
Xenopus laevis X80697
95324561
Protein Phosphatase regulatory 65k
Xenopus laevis X80698
95324561


GENE LOCUS DATA

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Gene Subtype Locus Species Genome Database Mouse Genome Database OMIM Locus Link
Protein Phosphatase catalytic alpha
Homo sapiens

176915
Protein Phosphatase catalytic beta
Homo sapiens

176916
Protein Phosphatase regulatory PPP2R5D Homo sapiens

601646 5528
Protein Phosphatase regulatory PPP2R5C Homo sapiens

601645 5527
Protein Phosphatase regulatory PPP2R5B Homo sapiens

601644 5526
Protein Phosphatase regulatory PPP2R5A Homo sapiens

601643 5525
Protein Phosphatase regulatory PPP2R5E Homo sapiens

601647 5529
Protein Phosphatase regulatory Ppp2r5e Mus musculus


26932
Protein Phosphatase regulatory Ppp2r5c Mus musculus


26931


Recoverin

Human Data
Source data from literature
on this protein can be obtained here.
Editor's Notes
Subunit Subunits Aminoacids Modifications





Mr / Weight Cofactors / Substrates




Exons Transcripts Regulatory Elements





Markers / RFLPs Primers Assignment




General Data


PROTEIN DATA

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Protein Subtype Locus Species EC-No. Swissprot PIR Prosite
Recoverin p26 RCV Bos taurus EC- P21457 A46129 PS00018
Recoverin CAR RCV1 Homo sapiens EC- P35243 JC1227 A37966 I53425 I54809 PS00018
Recoverin CAR Rcvrn Mus musculus EC- P34057


GENE DATA

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Gene Subtype Locus Species Genbank Unigene Medline
Recoverin p26 RCV Bos taurus M95858 M77094
91157004 92335166 92070564
Recoverin CAR RCV1 Homo sapiens AB001838 S43855 S45545 S62028 G15951 NM_002903 Hs.80539 97069555 96178432 92392330 92406381 93272873
Recoverin CAR Rcvrn Mus musculus X66196 NM_009038 Mm.4830 92339508


GENE LOCUS DATA

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Gene Subtype Locus Species Genome Database Mouse Genome Database OMIM Locus Link
Recoverin
Frq Drosophila melanogaster 0004120


Recoverin CAR RCV1 Homo sapiens 135477
179618 5957
Recoverin CAR Rcvrn Mus musculus
Rcvrn
19674


References
  1. Barbee,J.L., Deutscher,S.L., Loomis,C.R., and Burns,D.J. The cDNA sequence encoding human protein kinase C-zeta. 1993; Gene. 132: 305-306.
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  2. Coussens,L., Parker,P.J., Rhee,L., Yang Feng,T.L., Chen,E., Waterfield,M.D., Francke,U., and Ullrich,A. Multiple, distinct forms of bovine and human protein kinase C suggest diversity in cellular signaling pathways Multiple, distinct forms of bovine and human protein kinase C suggest diversity in cellular signaling pathways. 1986; Science. 233: 859-866.
    Link to PubMed
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  3. Erdel,M., Baier-Bitterlich,G., Duba,C., Isakov,N., Altman,A., Utermann,G., and Baier,G. Mapping of the human protein Kinase C-theta (PRKCQ) gene locus to the short arm of chromosome 10 (10p15) by FISH. 1995; Genomics. 25: 595-597.
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  4. Huppi,K., Siwarski,D., Goodnight,J., and Mischak,H. Assignment of the Protein Kinase C delta Polypeptide Gene (Prkcd) to Human Chromosome 3 and Mouse Chromosome 14. 1994; Genomics. 19: 161-162.
    Goto Top

  5. Jones,T.A., Barker,H.M., da Cruz,S., Mayer Jäckel,R.E., Hemmings,B.A., Spurr,N.K., Sheer,D., Cohen,P.T., da Cruz,S.E.F., and Mayer Jaekel,R.E. Localization of the genes encoding the catalytic subunits of protein phosphatase 2A to human chromosome bands 5q23-->q31 and 8p12-->p11.2, respectively. 1993; Cytogenet.Cell Genet. 63: 35-41.
    Link to PubMed
    Goto Top

  6. Mazzarella,R., Ciccodicola,A., Esposito,T., Arcucci,A., Migliaccio,C., Jones,C., Schlessinger,D., Durso,M., and Desposito,M. Human protein kinase C lota gene (PRKCI) is closely linked to the BTK gene in Xq21.3 - Brief report. 1995; Genomics. 26: 629-631.
    Goto Top

  7. McCright,B., Rivers,A.M., Audlin,S., and Virshup,D.M. The B56 family of protein phosphatase 2A (PP2A) regulatory subunits encodes differentiation-induced phosphoproteins that target PP2A to both nucleus and cytoplasm. 1996; J.Biol.Chem. 271: 22081-22089.
    Goto Top

  8. Montini,E., Rugarli,E.I., Vandevosse,E., Andolfi,G., Mariani,M., Puca,A.A., Consalez,G.G., Dendunnen,J.T., Ballabio,A., and Franco,B. A Novel Human Serine-Threonine Phosphatase Related To The Drosophila Retinal Degeneration C (Rdgc) Gene Is Selectively Expressed In Sensory Neurons Of Neural Crest Origin. 1997; Hum.Mol.Genet. 6: 1137-1145.
    Goto Top

  9. Newton,A. and Williams,D.S. Protein kinase C in rod outer segments. 1992; Invest.Ophthalmol.Vis.Sci. 33 (Suppl.): 874
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  10. Newton,A.C. and Williams,D.S. Does protein kinase C play a role in rhodopsin desensitization? 1993; Trends.Biochem.Sci. 18: 275-277.
    Goto Top

  11. Takai,Y., Kishimoto,A., Iwasa,Y., Kawahara,Y., Mori,T., and Nishizuka,Y. Calcium-dependent activation of a multifunctional protein kinase by membrane phospholipids Calcium-dependent activation of a multifunctional protein kinase by membrane phospholipids. 1979; J.Biol.Chem. 254: 3692-3695.
    Link to PubMed
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  12. Tay,A., Simon,J.S., Squire,J., Hamel,K., Jacob,H.J., and Skorecki,K. Cytosolic phospholipase A(2) gene in human and rat: Chromosomal localization and polymorphic markers. 1995; Genomics. 26: 138-141.
    Goto Top


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This site is maintained and edited by
Dr. rer. medic. Markus Preising, Dipl.Biol.
Molecular Genetics Laboratory

Department of Paediatric Ophthalmology, Strabismology and Ophthalmogenetics
University of Regensburg
Head: Prof. Dr. med. Birgit Lorenz