Scientific Databases
Protein Database

Recent update from: 25.04.2005

This page provides a listing of genes involved in retinal degenerations and their partners involved in biochemical pathways of the retina and RPE. It gives links to data extracted from the literature and databases on the internet.

Proteins Involved in Retinal Disorders Proteins Not Involved in Retinal Disorders
Proteins of the Visual Cascade

Controlling and Supplying the Visual Cascade
Recovery of cGMP and Cation Concentrations of the Dark State
Recovery and Supply of the Chromophore
Cellular Trafficking
  • Retinitis pigmentosa GTPase-Regulator(RPGR)

  • Retinitis pigmentosa GTPase-Regulator-interacting Protein (RPGRIP1)

  • Rab Escort Protein (REP1)

  • Myosin VIIa (MyoVIIa)

  • Regulator of G-Protein Signalling 9 (RGS9)

  • Regulator of G-Protein Signalling 9 anchor protein (R9AP)

  • Small GTP-binding protein Rab27a

  • Rab3A-interacting molecule (RIM1)

  • Ocular Albinism 1 Gene (OA1)

  • Chediak-Higashi Syndrome Protein 1 (CHS1)

  • Hermansky-Pudlak-Syndrome Proteins

    • pale ear (HPS1, ep )

    • Adaptor-3-Complex, b3A-subunit (ADTB3A)

    • HPS3

    • light ear (HPS4, le)

    • ruby eye (HPS5, ru)

    • ruby eye2 (HPS6, ru2)

    • Dysbindin (DTNBP1)

Proteins of the Cytoskeleton
  • Cadherin 3(CDH3)

  • Cadherin 23(CDH23)

  • Protocadherin 15(PCDH15)

  • Collagen 2, a-subunit 1 (COL2A1)

Proteins involved in Splicing
  • U4/U6-associated Splicing Factor (HPPRP3)

  • RNA Processing Factor 31 (PRPF31)

  • Precursor of mRNA Processing Protein 8 (PPRPC8)

Control by Modification of Proteins
  • Geranyl-Geranyl Transferases I (GGTaseI)

Maintaining the Structural Integrity of Retinal Cells and Tissues

Transcription Factors

Growth Factors
Proteins of Unknown Function Underlying Retinal Disorders

  • Tyrosinase (TYR)

  • Tyrosinase-related Protein 1 (TRP 1)

  • Membrane-associated Transport Protein (MATP)

  • Pink Eye Dilution Gene (P)

  • Melanocortin Receptor 1 (MC1R)

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Contact the editor
This site is maintained and edited by
Dr. rer. medic. Markus Preising, Dipl.Biol.
Molecular Genetics Laboratory
Department of Paediatric Ophthalmology, Strabismology and Ophthalmogenetics
University of Regensburg
Head: Prof. Dr. med. Birgit Lorenz