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Retina International		Scientific Newsletter
Contact the Editor	Abbreviations	Recent update from: 16.01.2011 This site is maintained and edited by Dr. rer. medic. Markus Preising, Dipl.Biol. Laboratory of Molecular Ophthalmology Department of Opthalmology Justus-Liebig-University, Giessen, Germany Head: Prof. Dr. med. Birgit Lorenz This site includes links which are off influence of Retina International and do not neccessarily reflect the opinion of Retina International. Therefore, we refrain from any responsibility for these external links.

Scientific

Newsletter

Abbreviations

Recent update from: 16.01.2011

This site is maintained and edited by
Dr. rer. medic. Markus Preising, Dipl.Biol.
Laboratory of Molecular Ophthalmology
Department of Opthalmology
Justus-Liebig-University, Giessen, Germany
Head: Prof. Dr. med. Birgit Lorenz

This site includes links which are off influence of Retina International and do not neccessarily reflect the opinion of Retina International. Therefore, we refrain from any responsibility for these external links.

α1-PI	α1-Proteinase Inhibitor	α2-M	α2-macroglobulin	βFGF	Basic Fibroblast Growth Factor
βGal	β-Galactosidase	11cRAl	11-cis-Retinaldehyde	11cRBA	11cis-retinyl-bromoacetat
11cRoi	11-cis-Retinoids	11cRol	11-cis-Retinol	11cRy	11-cis-Retinyl-ester
A2-E	Diretinal-Ethanolamine Derivate	AA	Aminoacids	AAV	Adeno Associated-Virus
AB	Antibody	ABR	Auditory-evoked Brainstem Response	ADH	Alcohol/Retinol Dehydrogenase
ADP	Adenosine-Di-Phosphate	AhR	Aromatic Hydrocarbon Receptor	AIP	Aryl Hydrocarbon Receptor-interacting Protein
AIPL1	Aryl Hydrocarbon Receptor-interacting Protein	AIRS	ABCR/IRBP/Rhodopsin/S-Antigen common promoter element	Ala	Alanin
Asn	Aspartic acid	Asp	Asparagin	ASP	Agouti Signalling Protein
ATP	Adenosine-Tri-Phosphate	ATP5B	ATP Synthase β-subunit, mitochondrial	atRA	all-trans-Retinoic Acid
atRAl	all-trans-Retinaldehyde	atRBA	all-trans-retinyl-bromoacetat	atRoi	all-trans Retinoids
atRol	all-trans-Retinol	atRy	all-trans-Retinylester	AV	Adenovirus
BACMK	N-tert-butoxycarbonyl-L-biocytin-α11-aminoundecanochloromethyl keton	BCE	Binding CRAlBP Element (PCE1 flanked by GCAGGA)	BCP	Blue Cone Pigment
BDNF	Brain-derived Neurotropic Factor	bHLH-zip	basic Helix-Loop-Helix Zipper	BiP	Ig-binding protein
BLOC	Biogenesis of Lysosome-related Organelles Complex	bp	Basepair	BRC	(3R)-3-[boc-lys(biotinyl)-O-]-all-trans-retinol chloroacetat
C/EBP	CAAT-Enhancer Binding Protein	Ca_v1.3	L-type voltage-gated Ca²⁺ channel 1.3	CaM	Calmodulin
cAMP	cyclic Adenosine Mono Phosphat	CBE	CRX-binding element	CBS2	Cystathionine-β-synthetase 2
CC	Connecting Cilium	CCD	Coiled-Coil Domain	CCM	Chemical Cleavage Method
cDNA	Complementary DNA	CFP	Cerulean fluorescent protein	cGMP	cyclic Guanosine Mono Phosphate
CHOP	CCAAT/enhancer-binding protein homologous protein	CLZ	Carboxy-terminal leucine zipper	cM	centi Morgan
CMV	Cytomegaly Virus	cNMP	cyclic Nucleotide Mono Phosphate	CNTF	Ciliary Neurotrophic Factor
COS	Cone Outer Segments	CPE	Corneal Pigment Epithelium	CRABP	Cellular Retinoic Acid-binding Protein
CRAlBP	Cellular Retinaldehyd-binding Protein	CRBP	Cellular Retinol-binding Protein	CRX	Cone Rod Homeobox gene
Cys	Cystein	d.p.c.	days post-coitum - days after copulation	DGGE	Denaturing Gradient Gel Electrophoresis
DHA	Docosahexanoic acid	DNA	Deoxyribo-Nucleic Acid	DOPA	Dopamine
dpf	days post fertilization	EAM	Encapsidated Adenovirus Minichromosome	ECL	Extracellular Loop
EF-hand	Domain in Ca²⁺-binding proteins	ELM	External Limiting Membrane	ELO	Proteins involved in elongation of fatty acids
ELOVL4	Elongation of Very Long Chain Fatty Acids-like Protein 4	EOG	Electro-oculo-gram	EORD	Early Onset (severe) Retinal Dystrophy
ER	Endoplasmatic Reticulum	ERG	Electroretinogram	FIGE	Field Inversion Gel Electrophoresis
FITC	Fluorescein-5-Isothiocyanate	FRET	Fluorescence Resonance Energy Transfer	FTH1	Ferritin Heavy-chain Gene
GAP	GTPase-activating Protein	GC	Guanylate Cyclase	GCAP	Guanylate Cyclase-activating Protein
GCL	Ganglion Cell Layer	GCP	Green Cone Pigment	GDF	GDI Displacement Factor
GDI	GDP Dissociation Inhibitor	GDP	Guanosine-Di-Phosphate	GDS	GDP Dissociation Inhibitor
GEF	Guanine-nucleotide Exchange Factor	GFP	Green Fluorescent Protein	GG	Geranylgeranyl
GGtase	Geranyl Geranyl Transferase (see also: RGGT)	GIP	G-Protein Inhibitor Protein	Gln	Glutamic acid
Glu	Glutamine	Gly	Glycine	GNAT	Transducin, α-subunit
GNB	Transducin, β-subunit	GNB/G	Guanine Nucleotide-binding Protein β/γ dimer	GNG	Transducin, γ-subunit
GNGT	Transducin, γ-subunit	GNT	Guanine Nucleotide-binding Protein, Transducin	GPCR	G-Protein Coupled Receptor
GPI	Glycosylphosphatidylinositol	GROD	Granular Osmiophilic Deposits	GTP	Guanosine-Tri-Phosphate
HMG1	High Mobility Group 1	HNF-1	Hepato Nuclear Factor 1	hpf	hours post fertilization
HSPB4	Alpha crystallin A chain (Heat-shock protein beta-4)	HSV	Herpes Simplex Virus	HVJ	Hemeagglutinating Virus of Japan
HWMC	High Molecular Weight Complex	ICL	Intracellular Loop	Ile	Isoleucine
ILM	Inner Limiting Membrane	IMH	Isomerohydrolase	IMP	Inosine monophosphate
INL	Inner Nuclear Layer	IP3	Inositol-triphosphate	IPE	Iris Pigment epithelium
IPM	Interphotoreceptor Matrix	IR	Immunoreactivity	IRBP	Interphotoreceptor Retinoid-binding Protein
ISL	Inner Segment Layer	IVS	Intervening Sequence = Intron	kb	Kilobase (1,000 basepairs)
kDa	Kilodalton	KID	RepA/Rep⁺ protein KID motif	lacZ	E. coli Lactose Operon Gene Z = β-Galactosidase
LCR	Locus Control Region	Leu	Leucine	LRAT	Lecithin Retinol Acyl Transferase
LRR	Leucine Rich Repeat	Lys	Lysine	mAB	Monoclonal Antibody
Mb	Megabase (1,000,000 basepairs)	Met	Methionine	MII	Metarhodopsin II
MLTV	Malattia leventinese	MOI	Multiplicity of Infection	mRNA	Messenger Ribonucleic Acid
mRPE65	RPE65, membrane bound	MTOC	Micro-Tubule Organizing Center	NADH	Nicotinamide Adenine Dinucleotide (reduced)
NADPH	Nicotinamide Adenine Dinucleotide Phosphate (reduced)	NBOC	N-boc-L-biocytinyl-11-aminoundeca chloromethyl keton	NFL	Nerve Fibre Layer
NLS	Nuclear Localization Signal	NLS_BP	Bipartite Nuclear Localization Signal	NMD	Nonsense Mediated Decay
NPC	Nuclear Pore Complex	NR2E3	Photoreceptor cell-specific nuclear receptor	NRE	NRL responsive element
nt	Nucleotide	OAT	Ornithine d-Aminotransferase	Oct	Octomer Family of Transcription Factors
OGT	O-linked N-acetylglucosamine transferase	OKR	Optokinetic Response	ONL	Outer Nuclear Layer
ORF	Open Reading Frame	OS	Outer Segment	otd	mouse homologue to OTX2
OTX2	Homeobox Gene	P-	Phosphorylated-	PATJ	PALS1-Associated Tight Junction protein
PBI	PDZ-binding interface	PBM	PDZ-binding motif	PC	Phosphatidylcholine
PCB	Photoreceptor Cell Bodies	PCL	Photoreceptor Cell Layer	PCR	Polymerase Chain Reaction
PDC	Phosducin	PDE	Phosphodiesterase	PDEA	Phosphodiesterase, αa-subunit
PDEB	Phosphodiesterase, β-subunit	PDED	Phosphodiesterase, δ-subunit	PDEG	Phosphodiesterase, γ-subunit
PDP	Pooled DNA PCR	PDZ	Post-synaptic density 95, Disc large, Zonula occludens - Motif	PE	Phosphatidylethanolamine
PEA3	Polyomavirus Enhancer Activator-3	PERK	double-stranded RNA-regulated protein kinase-like ER kinase	PFGE	Pulsed Field Gel Electrophoresis
pfu	Plaque Forming Units	Phe	Phenylalanine	PI	Phosphatidylinositol
PIP	Phosphatidyl-inositol-4-phosphate	PIP2	Phosphatidyl-inositol-4-5-bisphosphate	PIRE	Pineal Regulatory Element
PIS	Photoreceptor Inner Segments	PKA	Proteinkinase A	PKC	Proteinkinase C
P-loop	ATP/GTP-binding site motif A	PM	Plasmamembrane	POS	Photoreceptor Outer Segment
PP	Pyrophosphate, Diphosphate	PPI	Polyphosphoinositide	PPi	Inorganic Pyrophosphate
PR	Photoreceptor	PRA	Progressive Retina Atrophy	PRK	Protein kinase
PRKC	Protein Kinase C	Pro	Proline	PS	Phosphatidylserine
PSDR1	Prostate Short-Chain Dehydrogenase/Reductase 1	PUFA	Polyunsaturated Fatty Acids	RA	Retinoic Acid
rAAV	recombinant AAV	RAl	Retinaldehyde/Retinal	RAR	Retinoic-acid Receptor
RCC1	Ran GTPase Guanine Exchange Factor	rcd	rod-cone dystrophy	RCP	Red Cone Pigment
RCS	Royal College of Surgeons	RCV	Recoverin	RDH	11-cis-Retinol Dehydrogenase
REH	Retinylester Hydrolase	Ret-1/PCE	Photoreceptor Conserved Element	RFP	Arg-Phe-Pro Containing Protein
RGC	Retinal Ganglion Cells	RGGT	Rab Geranyl-Geranyl Transferase	RGR	RPE-retinal G-protein-coupled Receptor
RGS	Regulators of G-protein Signalling	RHC	Red Hair Colour	RHO	Rhodopsin
RHOK	Rhodopsin Kinase	RID	RPGR-interacting Domain	RIMLP	RPGR-interacting Motor-like Protein
RIS	Rod Inner Segment	RNA	ribo-Nucleic Acid	RNA\iß	Inhibiting RNA
Rol	Retinol	ROS	Rod Outer Segments	RPE	Retinal Pigmentepithelium
RRL	Rabbit Reticulocyte Lysate	RT-	Reverse Transcription	RXR	Retinoid X Receptor
Ry	Retinyl-ester	RYA	Retinylamine	SA	Serum Albumine
SA	Serum Albumin	SAG	S-antigen, Arrestin	SAP	Sphingolipid Activator Proteins
SCR	Sequence Conserved Region	SDR	Short-chain dehydrogenase/reductase	Ser	Serine
serpin	Serine Protease Inhibitor Supergene Family	SMC	Structural Maintenance of Chromosomes	snRNP	small nuclear Ribo-Nucleo-Protein
SRBP	Serum Retinol-binding Protein	sRPE65	RPE65, cytosol solubilized	SSCA	Single Strand Conformation Polymorphism Analysis
SSCP	Single Strand Conformation Polymorphism	SSR	Short Sequence Repeat	SU	Subunit
TCRP	t-complex-related proteins	TGN	Trans Golgi Network	Thr	Threonine
TIE	Translation Inhibitory Element	TIMP	Tissue Inhibitor of Metalloproteases	TLX	Homologue to the orphan receptor encoded by the Drosophila terminal/gap gene tailless
TM	Transmembrane	TMD	Transmembrane domain	TPI1	Triosephosphate isomerase
TPR	Tetratricopeptide Repeat	TREp	Artificial Palindromic Sequence	TRP	Tetratricopeptide Repeat
Trp	Tryptophane	Tsp	Tail Specific Protease	TTR	Transthyretin
TUBB2C	Tubulin beta-2C chain	TZ	Transition Zone	UPD	Uniparental Disomy
UPR	Unfolded Protein Response	UTR	Untranslated Region	v/t-SNARE	Vesicle/Target-Soluble N-ethylmaleimide-sensitive factor Acceptor Receptor
vit. A	Vitamin A	WGE	Wheat Germ Extract	WT	Wild Type
XMP	Xathosine monophosphate	Y2H	Yeast-2-Hybrid Assay	YAC	Yeast Artificial Chromosome
YFP	Yellow fluorescent protein

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